Occasionally, standard ERCP techniques are limited in the evaluation and treatment of difficult bile duct and pancreatic duct stones and assessment of indeterminate strictures.

An indeterminate stricture is a blockage that occurs in either the bile duct or pancreatic duct that may be suspicious for cancer without a definitive tissue diagnosis.

Historically, these patients may have undergone an invasive surgical resection without a tissue diagnosis. SpyGlass is also performed for the evaluation and management of common bile duct and pancreatic duct stones.